Trial on Vascular Inflammation in Atopic Dermatitis
NCT02926807 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 57
Last updated 2018-12-19
Summary
A total of 30 subjects with moderate to severe atopic dermatitis. Thirty subjects without AD matched for sex, age and coronary artery disease risk factor with the AD subjects will also be included. All subjects will undergo the following imaging procedures: a 18FDG-PET to quantify vascular inflammation in the ascending aorta and carotids and a MDCT to calculate the Agatston score. Skin and blood biomarkers will also be assessed.
Conditions
- Atopic Dermatitis
- Vascular Inflammation
- Coronary Atherosclerosis
Interventions
- OTHER
-
FDG-PET Scan
a 18FDG-PET to quantify vascular inflammation
- OTHER
-
MDCT
a MDCT to calculate the Agatston score
- OTHER
-
biopsy and blood collection
biopsy and blood collection to assess biomarkers
Sponsors & Collaborators
-
Montreal Heart Institute
collaborator OTHER -
Icahn School of Medicine at Mount Sinai
collaborator OTHER -
Innovaderm Research Inc.
lead OTHER
Principal Investigators
-
Innovaderm Research clinical site · Innovaderm Research clinical site
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2017-01-31
- Primary Completion
- 2018-11-30
- Completion
- 2018-11-30
Countries
- Canada
Study Locations
More Related Trials
-
Platelet Leukocyte Aggregates in Acute Cardiac Syndrome vs Healthy Volunteers
NCT01797016 ·Status: COMPLETED
-
Effect of Metal Skin Sensitivity on Restenosis After Stent Implantation
NCT00226525 ·Status: UNKNOWN ·Phase: NA
-
Radial Strain ECHO-Guided Implantation of Cardiac Resynchronization Therapy
NCT01603706 ·Status: COMPLETED ·Phase: NA
-
Implementation of Work in Progress (WIP) Sequences in Magnetic Resonance Imaging (MRI)
NCT01019226 ·Status: UNKNOWN
-
The Association of Platelet Function and Endothelial Function of the Brachial Artery
NCT00363818 ·Status: COMPLETED
-
Registry of Cardiovascular Disease Patients
NCT01759225 ·Status: ENROLLING_BY_INVITATION
-
Dotatate to Locate Coronary Plaques at High-risk of Myocardial Infarction
NCT05536960 ·Status: COMPLETED ·Phase: NA
-
The De-novo Use of Eculizumab in Presensitized Patients Receiving Cardiac Transplantation
NCT02013037 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Coronary CT Angiography to Invasive Coronary Angiography
NCT00146887 ·Status: UNKNOWN ·Phase: NA
-
Effects of Low Frequency Magnetic Field on Exercise Induced Angina
NCT01423422 ·Status: UNKNOWN
-
Autoantibodies and Clinical Symptoms in Infective Endocarditis Patients
NCT00562653 ·Status: UNKNOWN
-
Intracoronary Analysis of Cardiac Allograft Vasculopathy by Means of Optical Coherence Tomography
NCT02254668 ·Status: UNKNOWN ·Phase: PHASE4
-
"Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up
NCT00960817 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Assessment of Myocardial Viability Using Multidetector Computed Tomography
NCT00285064 ·Status: COMPLETED ·Phase: NA
-
Exploring the MEchanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and computationaL Fluid Dynamic
NCT02374775 ·Status: UNKNOWN
-
Doppler Assesment of Blood Flow in the Spiral Arteries
NCT01639989 ·Status: UNKNOWN
-
Adverse Myocardial and Vascular Side Effects of Immune Checkpoint Inhibitors
NCT04586894 ·Status: COMPLETED
-
Endothelial Function in Patients With Ectatic Compared to Normal Coronary Arteries
NCT00548457 ·Status: UNKNOWN
-
[68Ga]Ga-PentixaFor PET/CT in Acute Myocardial Inflammation
NCT05499637 ·Status: RECRUITING ·Phase: PHASE2
-
Quantitation of Left Ventricular Ejection Fraction Change From Early Exercise Gated Stress/Rest Tc-99m CZT-SPECT MPI
NCT02863952 ·Status: UNKNOWN ·Phase: NA
-
Coronary Artery Disease After Heart Transplantation
NCT03583229 ·Status: UNKNOWN ·Phase: NA
-
Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques
NCT00449306 ·Status: UNKNOWN
-
Macroscopic and Molecular Changes in Knee Muscular - Tendon Unit in Response to Acute Resistant Load
NCT03332693 ·Status: UNKNOWN ·Phase: NA
-
The Effects of External Counter Pulsation Therapy on Circulating Endothelial Progenitor Cells
NCT00272571 ·Status: COMPLETED ·Phase: NA
-
Clinical In-hospital Evaluation of the Usefulness of a New Multi-detector Computed Tomography Scanner From Arineta Ltd
NCT02616939 ·Status: UNKNOWN