sCD163 in PBC Patients - Assessment of Disease Severity and Prognosis
NCT02924701 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 168
Last updated 2022-08-12
Summary
Primary biliary cholangitis (PBC) is an autoimmune chronic liver disease, characterised by destruction of the small intrahepatic bile ducts. sCD163 is a macrophage activation marker shedded into plasma by macrophages in the liver. sMR is a soluble mannose receptor. The investigators want to investigate whether sCD163 and sMR correlate with disease severity in patients with PBC, and whether sCD163 and sMR can predict short term disease progression, changes in quality of life and death in these patients.
Conditions
- Primary Biliary Cirrhosis
- Liver Inflammation
Interventions
- OTHER
-
Blood samples, fibroscan and questionaires
Sponsors & Collaborators
-
University of Aarhus
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-09-30
- Primary Completion
- 2031-01-31
- Completion
- 2031-09-30
Countries
- Denmark
Study Locations
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