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Local Administration of Tranexamic Acid in Upper Gastrointestinal Hemorrhage

NCT02903017 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 114

Last updated 2018-03-06

No results posted yet for this study

Summary

Upper gastrointestinal hemorrhage is a frequently diagnosis in emergency departments. Although new drugs and endoscopic techniques were easily applied in various settings in this condition, the role of local administered therapies such as antifibrinolytic agents remain unclear. The investigators aimed to compare standard therapy (proton pump inhibitors, endoscopic treatments etc.) and standard therapy + local administered tranexamic acid in upper gastrointestinal hemorrhage in a double-blind, randomized trial.

Conditions

  • Gastrointestinal Hemorrhage
  • Tranexamic Acid
  • Emergency Department
  • Antifibrinolytic Agents

Interventions

DRUG

Tranexamic acid 5%

Via nasogastric tube, 100 mL

DRUG

Placebo

Via nasogastric tube, 100 mL

Sponsors & Collaborators

  • Kocaeli University

    lead OTHER

Principal Investigators

  • Nurettin Özgür Doğan, M.D., Assoc. Prof. · Kocaeli University, Faculty of Medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2018-03-31
Completion
2018-03-31

Countries

  • Turkey (Türkiye)

Study Locations

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Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02903017 on ClinicalTrials.gov