Severe Legionellosis Cases Admitted to Grenoble University Hospital, 2006-2011.
NCT02884700 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 82
Last updated 2016-08-31
Summary
The study aimed at further describing the epidemiological, clinical, diagnostic and prognostic features in legionellosis cases admitted to Grenoble University Hospital during the 2006-2011period. The investigators also tested lower respiratory samples collected from these patients during their routine medical care, using a number of molecular tools allowing determination of the involved Legionella species, the bacterial load, and the presence of antibiotic resistant mutants. Our primary goal was to define biological markers that could predict severity and outcome of infection in legionellosis cases requiring hospitalization.
Conditions
- Legionnaires' Disease
Interventions
- BIOLOGICAL
-
Real-time PCR testing of lower respiratory tract samples
qPCR and high-throughput DNA sequencing testing of lower respiratory tract samples collected routinely in patients with severe legionellosis
Sponsors & Collaborators
-
University Hospital, Grenoble
lead OTHER
Principal Investigators
-
Hélène Sabbah-Guillaume, Director · Direction of Research and Medical Innovation (DRCI)
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-09-30
- Primary Completion
- 2011-12-31
- Completion
- 2014-12-31
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