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Clinical Study of Relationship Between Granulocyte Activation, HDAC2 and Severe Asthma

NCT02881502 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2016-08-29

No results posted yet for this study

Summary

Program： Clinical Study of Relationship Between Granulocyte Activation, HDAC2 and Severe Asthma Aim：The early prediction of severe asthma, early intervention on the disease, reduce the family and the national finance.

design:This study is a single center randomized controlled trial designed by the Department of respiratory medicine, Xijing Hospital, as the main research unit.Compare the case group(severe asthma group and mild-and-moderate asthma group) and control group(healthy control group) by detecting the activity of MPO、NE、MMP-9 and ECP in the peripheral blood and the activity of HDAC2 in PBMCs of patients.

case:60

Case selection:

Inclusion criteria: age 18-75 years old; diagnosis of asthma was clear; informed consent was signed.

Exclusion criteria: poor compliance; cognitive ability is low; psychiatric disorders need to be combined with psychotropic medication.

Conditions

Interventions

OTHER

severe asthma group

No intervention

Sponsors & Collaborators

  • Xijing Hospital

    lead OTHER

Principal Investigators

  • Wu C gui, professor · Xijing Hospital

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-06-30
Primary Completion
2017-07-31
Completion
2017-07-31

Countries

  • China

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02881502 on ClinicalTrials.gov