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Clinical Characteristics, Treatment and Prognosis of Chest Tightness Variant Asthma

NCT03237221 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 76

Last updated 2020-10-27

No results posted yet for this study

Summary

Asthma, abbreviation for bronchial asthma, is one of the common chronic airways disease that threatens human health. Typical symptoms of asthma are recurrent wheezing, shortness of breath, chest tightness and cough, usually occurring at night or early morning. However, there are still some patients with only persistent clinical manifestations of chest tightness. Concerned about this group of patients, we presented a subgroup of bronchial asthma, namely, chest tightness variant asthma (CTVA). This asthma subgroup usually lacks asthma-specific clinical features such as wheezing, shortness of breath, wheezing, and therefore often misdiagnosed for a long time. In order to further understand the clinical characteristics, pathogenesis, and prognosis of patients with CTVA, we conducted a national multicenter observation study to further understand CTVA. Finally, we plan to clarify whether CTVA is a relatively independent asthma phenotype. Meanwhile, reducing misdiagnosis and perform an appropriate treatment of CTVA.

Conditions

  • Asthma
  • Chest Syndrome
  • Clinical Anxiety
  • Clinical Depression
  • Lung Function
  • Quality of Life
  • Eosinophilia
  • Nitric Oxide
  • Airway Responsiveness
  • Induced Sputum

Interventions

DRUG

Treat patient according to Global Initiative for Asthma (GINA) guideline

Treat patient according to Global Initiative for Asthma (GINA) guideline

Sponsors & Collaborators

  • Second Affiliated Hospital, School of Medicine, Zhejiang University

    lead OTHER

Principal Investigators

  • Huahao Shen · Second Affiliated Hospital, School of Medicine, Zhejiang University

Eligibility

Min Age
14 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-03-01
Primary Completion
2019-12-12
Completion
2020-10-23

Countries

  • China

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03237221 on ClinicalTrials.gov