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Association of Air Quality and Myocardial Infarction

NCT02880436 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12000

Last updated 2017-08-25

No results posted yet for this study

Summary

Besides classical cardiovascular risk factors such as smoking, obesity, elevated cholesterol levels and diabetes there are also acute factors potentially triggering acute coronary events. The impact of various substances and air pollution are described.

Particulate matter, especially with small particle size (\<2.5µm) has been shown to have a positive correlation with myocardial infarctions. However, other studies failed to show this correlation.

With respect to nitric oxydes the majority of published studies detected a significant correlation with myocardial infarction, too, although a highly ranked publication failed to show the same result. In addition data on the impact of sulfur dioxide and carbon monoxide concentration on cardiac events is very heterogeneous.

Published data indicates additive effects of age and other epidemiological variables suggesting the need of a multivariate analysis.

The rationale of the study is to test if the above mentioned air pollution factors have a significant and independent impact on the incidence of myocardial infarctions

Conditions

  • Acute Myocardial Infarction

Interventions

OTHER

air pollution

impact of various pollution agents above threshold and their correlation with acute myocardial infarctions are analyzed

Sponsors & Collaborators

  • Medical University of Graz

    lead OTHER

Principal Investigators

  • Dirk von Lewinski, MD · Dirk von Lewinski

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2017-06-30
Completion
2017-06-30

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02880436 on ClinicalTrials.gov