Effect of Schistosomiasis Mansoni on HIV Susceptibility and Female Genital Immunology
NCT02878564 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 34
Last updated 2016-10-27
Summary
The aim of this study is to assess the impact of Schistosoma mansoni infection and its treatment on genital immunology and HIV susceptibility in Ugandan women.
Conditions
- Schistosomiasis Mansoni
- HIV
Interventions
- DRUG
-
Praziquantel
40 mg/kg, PO (orally administered tablets)
Sponsors & Collaborators
-
UVRI-IAVI HIV Vaccine Program, Uganda
collaborator UNKNOWN -
University of Toronto
lead OTHER
Principal Investigators
-
Rupert Kaul, MD/PhD · University of Toronto
Study Design
- Allocation
- NA
- Purpose
- BASIC_SCIENCE
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-03-31
- Primary Completion
- 2016-10-31
- Completion
- 2016-10-31
Countries
- Uganda
Study Locations
More Related Trials
-
Childhood Schistosomiasis: a Novel Strategy Extending the Benefits/Reach of Antihelminthic Treatment
NCT02495909 ·Status: COMPLETED
-
An Open Label Dose Finding Safety and Efficacy in Children and Infants Infected With Schistosomiasis (S.Mansoni)
NCT02806232 ·Status: COMPLETED ·Phase: PHASE2
-
Possible Efficacy and Safety of Mebendazole in Patients With Ulcerative Colitis Treated With Mesalamine
NCT06335160 ·Status: RECRUITING ·Phase: NA
-
Prevention of Female Genital Schistosomiasis (FGS) in Rural High-endemic South Africa
NCT01154907 ·Status: UNKNOWN
-
Safety and Efficacy of Drug Combinations Against Schistosomiasis
NCT01050374 ·Status: COMPLETED ·Phase: NA
-
Schistosoma Mansoni in Mwanza Region, Tanzania
NCT02162875 ·Status: COMPLETED ·Phase: NA
-
Repeated Controlled Human Schistosoma Mansoni Infection
NCT05085470 ·Status: COMPLETED ·Phase: NA
-
Health Benefits of Repeated Treatment in Pediatric Schistosomiasis
NCT01424410 ·Status: COMPLETED
-
Evaluation of Strategies for Improved Uptake of Preventive Treatment for Intestinal Schistosomiasis
NCT01869465 ·Status: UNKNOWN ·Phase: NA
-
Empiric Therapy of Helminth Co-infection to Reduce HIV-1 Disease Progression
NCT00507221 ·Status: COMPLETED ·Phase: NA
-
Evaluation of the Use of a Urin Test Strip to Determine the Spread of Schistosoma Infections in Areas Where Schistosomiasis Infections Are Low in Kenya
NCT00463307 ·Status: COMPLETED
-
Treatment of Female Genital Schistosomiasis (FGS) With Praziquantel: A Proof-of-Concept Study
NCT04115072 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Clinical Evaluation of Ujiplus® Against Schistosoma Mansoni
NCT04679831 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
NCT00001645 ·Status: RECRUITING
-
A Randomised Trial of Artesunate-sulfamethoxypyrazine/Pyrimethamine Versus Praziquantel for the Treatment of S. Mansoni
NCT01054651 ·Status: COMPLETED ·Phase: PHASE3
-
Using Community-Based Volunteers to Reach Non-Enrolled School Aged Children Through Community-Directed Treatment of Schistosomiasis in School-Aged Children in Rural Northern Ghana
NCT00463931 ·Status: COMPLETED
-
Evaluation of Praziquantel Dosage for Treatment of Schistosomiasis in Brazil
NCT00403611 ·Status: COMPLETED ·Phase: PHASE4
-
Schistosoma Haematobium Infections and Praziquantel
NCT01558336 ·Status: COMPLETED ·Phase: PHASE3
-
Epidemiology and Control of Mansonella Perstans Infection in Uganda
NCT00215280 ·Status: COMPLETED ·Phase: NA
-
Single-sex Controlled Human Schistosomiasis Infection: Safety and Dose Finding
NCT02755324 ·Status: COMPLETED ·Phase: NA
-
Monitoring Drug Efficacy and Anthelmintic Resistance in Soil-transmitted Helminth Programs
NCT04177654 ·Status: COMPLETED
-
Single-sex Female Controlled Human Schistosomiasis Mansoni Infection
NCT04269915 ·Status: COMPLETED ·Phase: NA
-
Evaluation of an AI-DP for STH Deworming Programs: a Study Protocol
NCT06055530 ·Status: UNKNOWN
-
Monitoring Schistosome Hybrids Under Under Praziquantel Pressure
NCT04635553 ·Status: UNKNOWN
-
Schistosome and Intestinal Worm Infections and Malaria Morbidity Among School and Pre-school Children in, Tanzania
NCT00347113 ·Status: COMPLETED ·Phase: NA