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Screening in Oculopharyngeal Muscular Dystrophy

NCT02877784 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 8

Last updated 2020-03-27

No results posted yet for this study

Summary

Oculopharyngeal muscular dystrophy (OPMD) is a rare myopathic disease that results in progressive degeneration of the oral and pharyngeal muscular, resulting in severe dysphagia and dysarthria. OPMD is considered a rare disease; therefore, limited research is available on the natural progression of the disease or the utility of biomarkers to identify swallowing impairment. The aim of this study is:

1. To identify accurate, reliable and non-invasive clinical markers of swallowing impairment
2. To determine the discriminate ability of these markers to identify impairments in swallow safety and swallowing efficiency.

Conditions

  • Oculopharyngeal Muscular Dystrophy

Interventions

PROCEDURE

Videofluoroscopic swallowing study

Videofluoroscopic swallowing study will be performed to measure the oropharyngeal swallowing.

OTHER

Functional Oral Intake Scale

The Functional Oral Intake Scale (FOIS) will be used for participants to report their food intake habits.

OTHER

Eating Assessment Tool-10

The Eating Assessment Tool-10 will be used for participant reporting of swallowing system severity.

Sponsors & Collaborators

  • University of Florida

    lead OTHER

Principal Investigators

  • Emily Plowman, PhD · University of Florida

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-10-31
Primary Completion
2017-08-31
Completion
2017-08-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02877784 on ClinicalTrials.gov