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The Role of Cardiac Mechanics, Biomarkers and Frailty in Aortic Stenosis

NCT02856620 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 450

Last updated 2024-11-22

No results posted yet for this study

Summary

The role of cardiac mechanics, circulating biomarkers and frailty in predicting outcomes in patients with aortic stenosis after aortic valve replacement (SCRABLES -The 2-Parts Study) Part I: Observational study to characterize phenotypes, structural alterations and biomarkers profiles in a broad spectrum of patients with aortic stenosis and heart failure with preserved ejection fraction (HFpEF).

Part II: Prospective cohort study to characterize patients' phenotypes, cardiac structural alterations, circulating biomarkers and frailty in order to optimize risk stratification and patient selection for aortic valve intervention.

Conditions

Interventions

OTHER

Observational only

Observational only

Sponsors & Collaborators

  • Christine Henri

    lead OTHER

Principal Investigators

  • Christine Henri, MD · Montreal Heart Institute

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-07-31
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02856620 on ClinicalTrials.gov