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Perceptual Retraining to Reduce Suicide Risk

NCT02845700 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 13

Last updated 2019-01-14

Study results available
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Summary

The study will use a prospective design consisting of three phases. The phases are:

1. the development of the perceptual retraining treatment (PRT),
2. the evaluation of the treatment's feasibility and acceptability, and
3. an assessment of its efficacy.

During the third phase, a pilot study will be conducted in which participants will be randomly assigned to either PRT or a waitlist control group in order to assess efficacy. Diagnostic information and eligibility criteria will be assessed using the Structured Clinical Interview for Diagnostic and Statistical Manual (DSM) 4th ed. (SCID) and the Clinician Administered PTSD Scale for DSM-5 (CAPS-5).

Conditions

  • Perceptual Olfactory Bias

Interventions

BEHAVIORAL

Perceptual Retraining Treatment

Perceptual retraining involves the systematic presentation of diluted malodors (i.e., odors perceived as threatening). For each individual, vials on either side of a pre-determined and ideographic detection threshold will be presented. During the retraining, participants will be given feedback to shift their bias away from the malodorous target stimuli. For example, in the context of diluted solutions participants will be given the feedback that they are "correct" when a "neutral" response is given to solutions that are above the starting threshold (stronger malodor) and "incorrect" when a target is endorsed that is below the starting threshold (weaker malodor).

BEHAVIORAL

Sham Neutral training

Control condition using systematic presentation of diluted neutral-neutral odor pairs.

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED

  • Southeast Louisiana Veterans Health Care System

    collaborator FED

  • Florida State University

    lead OTHER

Principal Investigators

  • Wen Li, PhD · Florida State University

  • Laurel Franklin, PhD · Southeastern Louisiana Veterans Health Care System

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2016-09-30
Completion
2016-09-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02845700 on ClinicalTrials.gov