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Therapeutic Antibodies Against Prion Diseases From PRNP Mutation Carriers

NCT02837705 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 213

Last updated 2023-05-24

No results posted yet for this study

Summary

The human Prion diseases can be classified into sporadic, acquired and inherited forms. Inherited forms usually manifest in higher age so there have to be factors preventing Prion propagation in young mutation carriers. Antibodies against the flexible tail of Prions have been shown to be protective in mice. The investigators intend to screen mutation carriers and controls for the presence of Prion autoantibodies.

Conditions

  • Prion Diseases

Interventions

OTHER

blood draw

Sponsors & Collaborators

  • University of Zurich

    lead OTHER

Eligibility

Min Age
1 Year
Max Age
99 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-09-01
Primary Completion
2018-10-15
Completion
2019-03-01

Countries

  • United States
  • Austria
  • Germany
  • Israel
  • Italy
  • Slovakia
  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02837705 on ClinicalTrials.gov