Clinical Evaluation of Patients With X-linked Retinoschisis
NCT02331173 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 66
Last updated 2017-11-17
Summary
The purpose of this study is to evaluate subjects with X-linked retinoschisis in a clinical setting to collect data on disease progression.
Conditions
- X-linked Retinoschisis
- XLRS
Interventions
- DRUG
-
Dorzolamide 2% TID or brinzolamide 1% TID
Dosing of all medications will be based upon standard of care. Standard dosing for the treatment of pediatric and adult patients with XLRS is as follows: * Topical dorzolamide 2% three times per day * Topical brinzolamide 1% three times per day
Sponsors & Collaborators
-
Foundation Fighting Blindness
collaborator OTHER -
Beacon Therapeutics
lead INDUSTRY
Principal Investigators
-
Matt Feinsod, MD · Applied Genetics Technologies Corporation
Eligibility
- Min Age
- 7 Years
- Sex
- MALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-11-30
- Primary Completion
- 2016-10-31
- Completion
- 2016-10-31
Countries
- United States
Study Locations
More Related Trials
-
ERG/5-HTP in Fragile X Syndrome (FXS)
NCT05030129 ·Status: COMPLETED ·Phase: PHASE2
-
4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)
NCT04517149 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Riluzole in Fragile X Syndrome
NCT00895752 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy of a Single Subretinal Injection of JWK002 Gene Therapy in Subjects With X-linked Retinoschisis(XLRS)
NCT06345898 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)
NCT07185256 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome
NCT04977986 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of RO4917523 in Patients With Fragile X Syndrome
NCT01517698 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of RO4917523 in Pediatric Patients With Fragile X Syndrome
NCT01750957 ·Status: COMPLETED ·Phase: PHASE2
-
An Initial Study of AZD7325 in Adults With Fragile X Syndrome
NCT03140813 ·Status: COMPLETED ·Phase: PHASE1
-
A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome
NCT01894958 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Assess the Tolerability of a Single Dose of STX107 in Adults With Fragile X Syndrome
NCT01325740 ·Status: SUSPENDED ·Phase: PHASE2
-
Open Label Extension to Assess the Long-Term Safety and Tolerability of ZYN002 in Children and Adolescents With FXS
NCT03802799 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE2/PHASE3
-
Biomarker Testing and DNA Collection in Subjects Participating in Protocol 22001
NCT00823368 ·Status: COMPLETED
-
An Open Label Extension Study in Subjects With Fragile X Syndrome
NCT01555333 ·Status: TERMINATED ·Phase: PHASE3
-
A Study of BPN14770 in Male Adults (Aged 18 to 45) With Fragile X Syndrome
NCT05358886 ·Status: COMPLETED ·Phase: PHASE3
-
Investigation of Sulindac (HLX-0201) and Gaboxadol (HLX-0206) in Male Fragile X Syndrome Patients Aged 13-40
NCT04823052 ·Status: WITHDRAWN ·Phase: PHASE2
-
Examining the Effect of Burosumab on Muscle Function
NCT04146935 ·Status: COMPLETED ·Phase: PHASE4
-
Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)
NCT01175239 ·Status: UNKNOWN ·Phase: NA
-
ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis
NCT05878860 ·Status: RECRUITING ·Phase: PHASE3
-
Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)
NCT07209462 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of KRN23 in Subjects With X-linked Hypophosphatemic Rickets/Osteomalacia
NCT02181764 ·Status: COMPLETED ·Phase: PHASE1
-
A Clinical Study to Evaluate the Efficacy and Safety of MIN-102 (IMP) in Male AMN Patients.
NCT03231878 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Disease Progression in Women With X-linked Adrenoleukodystrophy
NCT06178120 ·Status: RECRUITING
-
Low-Dose Sirolimus to Increase Hematopoietic Function in Patients With RUNX1 Familial Platelet Disorder
NCT06261060 ·Status: RECRUITING ·Phase: PHASE2
-
Acamprosate in Youth With Fragile X Syndrome
NCT01300923 ·Status: COMPLETED ·Phase: PHASE2