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The Prognostic Value of Pupil Near Response in UWS Patients

NCT02832492 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2022-08-04

No results posted yet for this study

Summary

Previous studies suggest that the stimulus of pupil near response (PNR) may be a conscious perception of a blurred image. Moreover, PNR is a reflex that can be objectively observed and with no motor output, suggesting it might be a more convenient index for consciousness evaluation and consciousness recovery in patients with disorders of consciousness (DOC). We thus hypothesized that PNR+ patients (patients show PNR during the assessment) would have better prognosis than PNR- patients (patients fail to show PNR during the assessment).Based on this hypotheis, researchers will assess pupil near response in patients with unresponsive wakefulness syndrome (UWS) and compare the prognosis difference between PNR+ patients and PNR- patients to assess its prognosis value.

Conditions

  • Vegetative State

Interventions

BEHAVIORAL

pupil near response

Sponsors & Collaborators

  • Wentao Zeng

    lead OTHER

Eligibility

Min Age
6 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-10-29
Primary Completion
2016-02-10
Completion
2016-02-10

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02832492 on ClinicalTrials.gov