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Genetic Markers of Cardiovascular Disease in Epilepsy

NCT02824822 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 600

Last updated 2025-09-08

No results posted yet for this study

Summary

Epilepsy is a common condition which affects over 3 million people in the US. Patients with uncontrolled epilepsy have a lifetime risk of sudden unexpected death (SUDEP) of 35%, which is greatest in those under 40 years of age. The exact mechanisms and causes are not understood but can be due to underlying conditions which affect the heart and brain, which may lead to dangerous heart rhythms and death. Some of these conditions which affect heart and brain have an identifiable genetic cause. This study aims to identify known genetic causes of heart rhythm and sudden death related disorders in patients with epilepsy.

Conditions

Sponsors & Collaborators

Principal Investigators

  • Virend K. Somers, MD PhD · Mayo Clinic

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-05-31
Primary Completion
2031-12-31
Completion
2031-12-31

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02824822 on ClinicalTrials.gov