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Prospective Research Rare Kidney Stones (ProRKS)

NCT02780297 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 220

Last updated 2025-08-06

No results posted yet for this study

Summary

The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of renal dysfunction in these disorders.

Conditions

  • Hyperoxaluria
  • Cystinuria
  • Dent Disease
  • Lowe Syndrome
  • Adenine Phosphoribosyltransferase Deficiency

Sponsors & Collaborators

Principal Investigators

  • John Lieske, MD · Mayo Clinic

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-05-31
Primary Completion
2026-07-31
Completion
2026-07-31

Countries

  • United States
  • Canada
  • Iceland
  • Israel

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02780297 on ClinicalTrials.gov