MedTrace Logo

Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch

NCT02769910 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2016-11-22

No results posted yet for this study

Summary

The purpose of this project is to investigate the effect of capsaicin-induced neurogenic inflammation with three different intensities on itch subsequently induced by histamine and cowhage. The hypothesis is that capsaicin-induced pre-established neurogenic inflammation significantly increases susceptibility to itch provocations with cowhage and histamine.

Conditions

Interventions

DRUG

Capsaicin 24 Hours

Dermal patches for transdermal application of Capsaicin, applied for 24 hours

DRUG

Capsaicin 1 Hour

Dermal patches for transdermal application of Capsaicin, applied for 1 hour

OTHER

Qutenza Demo Patch

Dermal patches mimicking active Qutenza patches. Used as control in comparison of Capsaicin efficacy. Applied for 24 hours.

Sponsors & Collaborators

  • Hjalte Holm Andersen

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2016-05-31
Primary Completion
2016-07-31
Completion
2016-07-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02769910 on ClinicalTrials.gov