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The Effect of Anesthetics Agents on Vascular Injury and Level of Syndecan-1 During Knee Surgery

NCT02756715 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2020-02-28

No results posted yet for this study

Summary

Ischeic reperfusion injury lead to a cellular dyfunction and increase in soluble glycocalyx of blood flow. syndecan-1 was a marker of glycocalyx.

The purpose of this study is to prove the variation of level of serum syndecan-1 between preoperative and postoperative period.

Conditions

  • Ischemia

Interventions

DRUG

propofol group

Patient will be anesthetized by using propofol infusion during operation.

DRUG

Desflurane group

Patient will be anesthetized by using desflurane inhalation during operation.

Sponsors & Collaborators

  • Konkuk University Medical Center

    lead OTHER

Principal Investigators

  • Seong-Hyop Kim, M.D,Ph.D · Konkuk University Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-05-30
Primary Completion
2018-03-26
Completion
2020-02-27

Countries

  • South Korea

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02756715 on ClinicalTrials.gov