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A Comparison of Two Treatments for CRPS and Changes in Resting-State Connectivity of Cerebral Networks.

NCT02753335 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 42

Last updated 2023-05-11

No results posted yet for this study

Summary

The intention of this trial is to investigate whether combined Graded Motor Imagery (GMI) and Desensitization (D) among patients with CRPS is clinically more effective than only D and to study changes in connectivity in the Default Mode Network before and after treatment.

Conditions

  • Complex Regional Pain Syndrome

Interventions

BEHAVIORAL

GMI and Desensitization

Graded Motor Imagery (GMI) is used to treat chronic pain conditions and movement problems related to alterations in the nervous system such as CRPS, postamputation limb pain and back pain. The patient is trained in monitored steps. The three treatment components include left/right discrimination training, motor imagery exercises and mirror observations of the unaffected limb, appearing as the affected limb. They are performed sequentially, but require a flexible approach to suit the individual patient. The imagined movements have been demonstrated to activate motor cortical areas similar to those activated in the actual execution of that movement. Desensitization (D) is used to decrease hyperalgesia by repeated tactile stimulation of the affected area with various materials.

BEHAVIORAL

Desensitization

Desensitization (D) is used to decrease hyperalgesia and allodynia by repeated tactile stimulation of the affected area with various materials.

Sponsors & Collaborators

  • University Hospital of North Norway

    collaborator OTHER

  • University of Tromso

    lead OTHER

Principal Investigators

  • Gunnvald Kvarstein, PhD · University of Tromso

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2023-12-31
Completion
2024-12-31

Countries

  • Norway

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02753335 on ClinicalTrials.gov