Exercise and Oscillatory Positive Expiratory Pressure Therapy in Cystic Fibrosis
NCT02750722 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16
Last updated 2017-01-25
Summary
The investigators aim to compare a single bout of moderately intense cycling exercise incorporating Flutter® breathing maneuvers with a single bout of moderately intense cycling exercise alone on sputum viscoelasticity (primary endpoint) and the diffusion capacity of the lungs in adult patients with cystic fibrosis.
The investigators further aim to analyze the short-term variability of resting diffusion capacity of carbon monoxide (DLCO) and nitric oxide (DLNO) in patients with cystic fibrosis.
Conditions
Interventions
- DEVICE
-
Flutter®
Acute exercise with Flutter® breathing therapy.
- DEVICE
-
No Flutter®
Acute exercise without Flutter® breathing therapy.
Sponsors & Collaborators
-
University of Zurich
lead OTHER
Principal Investigators
-
Thomas Radtke, PhD · University of Zurich
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-05-31
- Primary Completion
- 2017-01-19
- Completion
- 2017-01-19
Countries
- Switzerland
Study Locations
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