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The Effects of Long Term Inhalation of Hypertonic Saline in Subjects With Cystic Fibrosis

NCT00271310 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 164

Last updated 2006-10-09

No results posted yet for this study

Summary

The effect of long term inhalation of hypertonic saline in subjects with cystic fibrosis on lung function, incidence of respiratory tract infections, quality of life, quantitative microbiology and sputum cytokine profile. The hypothesis is that regular inhalation of nebulised hypertonic saline will have a beneficial effect on lung function and other clinical outcomes with no adverse effects on infection and inflammation in adults and children with cystic fibrosis.

Conditions

Interventions

DRUG

hypertonic saline

Sponsors & Collaborators

  • Cystic Fibrosis Foundation

    collaborator OTHER

  • National Health and Medical Research Council, Australia

    collaborator OTHER

  • Cystic Fibrosis Trust

    collaborator OTHER

  • Royal Prince Alfred Hospital, Sydney, Australia

    lead OTHER

Principal Investigators

  • Peter T P Bye, PhD · Royal Prince Alfred Hospital, Sydney, Australia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
6 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2000-09-30
Completion
2003-11-30

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00271310 on ClinicalTrials.gov