One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection

Summary

The purpose of this study is to compare the outcomes of two different treatment options commonly used to manage periprosthetic joint infection (PJI), an infection around the artificial knee or hip.

Conditions

• Surgical Site Infection

Interventions

PROCEDURE

One-stage exchange joint replacement surgery

PROCEDURE

Two-stage exchange joint replacement surgery

Sponsors & Collaborators

• The Cleveland Clinic

  collaborator OTHER

• Hospital for Special Surgery, New York

  collaborator OTHER

• Rothman Institute at Thomas Jefferson University

  collaborator UNKNOWN

• Midwest Orthopaedics Rush University Medical Center

  collaborator UNKNOWN

• Vanderbilt University

  collaborator OTHER

• Emory University

  collaborator OTHER

• University of Iowa

  collaborator OTHER

• Carilion Clinic

  collaborator OTHER

• University of Southern California

  collaborator OTHER

• Ochsner Health System

  collaborator OTHER

• Cleveland Clinic Florida

  collaborator OTHER

• University of Utah

  collaborator OTHER

• University of California, San Francisco

  collaborator OTHER

• OrthoCarolina Research Institute, Inc.

  lead OTHER

Principal Investigators

• Thomas K Fehring, MD · Attending Hip & Knee Surgeon

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-05-18

Primary Completion

2024-12-31

Completion

2026-01-07

Countries

• United States

Study Locations