In Vivo EGFR Molecular Classification and Treatment Response
NCT02717221 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 102
Last updated 2025-04-02
Summary
The investigators developed 18F-MPG as a targeted molecular imaging agent for noninvasive and repeatable detecting EGFR-activating mutational status. And use 18F-MPG to monitor EGFR-TKIs and chemotherapy treatment efficiency.
Conditions
- Molecular Imaging
Interventions
- OTHER
-
18F-MPG
N-(3-chloro-4-fluorophenyl)-7-(2-(2-(2-(2-\[18F\] fluoroethoxy) ethoxy) ethoxy) ethoxy)-6-methoxyquinazolin-4-amine (18F-MPG)
Sponsors & Collaborators
-
Harbin Medical University
lead OTHER
Principal Investigators
-
Baozhong Shen, M.D. · The Fourth Hospital of Harbin Medical University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-11-30
- Primary Completion
- 2019-12-31
- Completion
- 2019-12-31
Countries
- China
Study Locations
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