Impact of Helminth Infections During Pregnancy on Humoral Vaccine Immunogenicity in Infants
NCT02714348 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 323
Last updated 2016-03-21
Summary
Helminth infection is associated with low vaccine immunogenicity. Pregnant women are particularly sensitive to helminth infection.
Since most vaccines are given shortly after birth, an effect of parasites on infant immunogenicity is of particular concern. Therefore, within this study the investigators aim to investigate if maternal infection influences vaccine immunogenicity in the newborn.
Conditions
- Maternal Infection Affecting Newborn
Interventions
- OTHER
-
Effect of helminth infection on vaccine immunogenicity
Observational; immunology
Sponsors & Collaborators
-
University Hospital Tuebingen
collaborator OTHER -
Centre de Recherche Médicale de Lambaréné
lead OTHER
Principal Investigators
-
Akim A Adegnika, Md, PhD · Centre de Recherche Médicale de Lambaréné
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-02-28
- Primary Completion
- 2016-09-30
- Completion
- 2016-09-30
More Related Trials
-
Intervention to Promote Childhood Vaccinations and Influence Vaccination Attitudes
NCT05425823 ·Status: COMPLETED ·Phase: NA
-
Testing if BCG (Bacille Calmette-Guérin) Vaccination Can Induce Innate Immune Training in Adult People Above 50 Years of Age in Guinea-Bissau
NCT02953327 ·Status: COMPLETED ·Phase: PHASE4
-
Measles and BCG Vaccines for Mother and Child
NCT04899765 ·Status: RECRUITING ·Phase: PHASE4
-
Long Term Effects of BCG Vaccination on Infectious and Immune Mediated Diseases
NCT05387655 ·Status: ACTIVE_NOT_RECRUITING
-
A Study of MVA85A in Healthy Infants
NCT00953927 ·Status: COMPLETED ·Phase: PHASE2
-
Dose-Defining Safety and Immunogenicity Study of MTBVAC in South African Neonates
NCT03536117 ·Status: COMPLETED ·Phase: PHASE2
-
T-Cell Turnover Following Vaccination With MVA85A
NCT00548444 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Immunogenicity, and Impact of MVA85A, on the Immunogenicity of the EPI Vaccines
NCT00480454 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of the Safety and Immunogenicity of MVA85A in Healthy Gambian Volunteers
NCT00423839 ·Status: COMPLETED ·Phase: PHASE1
-
VISTA: Vaccinator-Initiated Screening and TAilored Counseling for Reducing Vaccine Hesitancy
NCT04421586 ·Status: COMPLETED ·Phase: NA
-
A Study of MVA85A in Healthy Children and Infants
NCT00679159 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of GC3107(BCG Vaccine) in Healthy Infants
NCT03947138 ·Status: COMPLETED ·Phase: PHASE3
-
Humoral and Cellular Immunity of Low and High-responders After Tick-borne Encephalitis Vaccination
NCT00804219 ·Status: COMPLETED ·Phase: PHASE4
-
Can BCG Vaccination at First Health-facility Contact Reduce Early Infant Mortality?
NCT04658680 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
Revaccination of Young Children With Bacille Calmette Guerin (BCG) Vaccine
NCT00126217 ·Status: TERMINATED ·Phase: PHASE4
-
BCG Vaccination Scar Formation in Children Under Five Years :Factors Affecting Its Formation and Subsequent Adverse Effects .
NCT03548233 ·Status: UNKNOWN ·Phase: NA
-
Prophylactic Antibiotics in Measles
NCT00168532 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Previously Received BCG
NCT00427830 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers Who Have Received BCG Immunisation 1 Month Previously
NCT00427453 ·Status: COMPLETED ·Phase: PHASE1
-
Induction of Immunity Against Measles in Pediatric Liver Transplant Recipients
NCT01770119 ·Status: RECRUITING ·Phase: PHASE4
-
A Second Dose of Measles Vaccine (MV) in the Second Year of Life
NCT02943681 ·Status: COMPLETED ·Phase: NA
-
A Phase I Study of the Safety and Immunogenicity of a Recombinant MVA Vaccine Encoding a Secreted Antigen From M. Tuberculosis, Antigen 85A, Delivered Intradermally by a Needle Injection in Healthy Volunteers.
NCT00423566 ·Status: COMPLETED ·Phase: PHASE1
-
Trial to Investigate the Effect of Schistosoma Mansoni Infection on the Response to Vaccination With MVA85A in BCG-vaccinated African Adolescents
NCT02178748 ·Status: COMPLETED ·Phase: PHASE2
-
Measles Vaccine: Is There a Protective Role in COVID 19 Pandemic?
NCT04445610 ·Status: UNKNOWN
-
Measles Vaccination at Health System Contacts
NCT04220671 ·Status: ENROLLING_BY_INVITATION ·Phase: PHASE4