Arsenic Trioxide and Itraconazole in Treating Patients With Advanced Basal Cell Cancer
NCT02699723 · Status: WITHDRAWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL
Last updated 2020-10-22
Summary
This pilot clinical trial studies how well arsenic trioxide and itraconazole work in treating patients with basal cell cancer that has spread to other places in the body and usually cannot be cured or controlled with treatment. Drugs used in chemotherapy, such as arsenic trioxide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Itraconazole may help treat fungal infections in patients with basal cell cancer. Giving arsenic trioxide with itraconazole may work better in treating basal cell cancer.
Conditions
- Skin Basal Cell Carcinoma
Interventions
- DRUG
-
Arsenic Trioxide
Given PO
- DRUG
-
Itraconazole
Given PO
- OTHER
-
Laboratory Biomarker Analysis
Correlative studies
Sponsors & Collaborators
-
Jean Yuh Tang
lead OTHER
Principal Investigators
-
Jean Tang · Stanford Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2020-12-31
- Primary Completion
- 2021-09-30
- Completion
- 2021-09-30
- FDA Drug
- Yes
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