Carboxyamidotriazole and Ketoconazole in Treating Patients With Advanced Cancers
NCT00003249 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2013-02-07
Summary
Phase I trial to study the effectiveness of carboxyamidotriazole and ketoconazole in treating patients with advanced cancers. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
Conditions
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
carboxyamidotriazole
- DRUG
- DRUG
-
ketoconazole
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Mark J. Ratain, MD · University of Chicago
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-05-31
- Primary Completion
- 2001-12-31
Countries
- United States
Study Locations
More Related Trials
-
Irinotecan and Carboplatin as Upfront Window Therapy in Treating Patients With Newly Diagnosed Intermediate-Risk or High-Risk Rhabdomyosarcoma
NCT00077285 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma
NCT00003776 ·Status: COMPLETED ·Phase: PHASE2
-
Decitabine in Treating Patients With Melanoma or Other Advanced Cancer
NCT00002980 ·Status: COMPLETED ·Phase: PHASE1
-
Advanced or Recurrent Solid Tumors Treated With SHetA2
NCT04928508 ·Status: RECRUITING ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Metastatic or Unresectable Solid Tumors
NCT00058253 ·Status: COMPLETED ·Phase: PHASE1
-
Chemotherapy in Treating Patients With Refractory Advanced Solid Tumors or Hematologic Cancer
NCT00004065 ·Status: COMPLETED ·Phase: PHASE1
-
BMS-188797 and Carboplatin in Treating Patients With Advanced Nonhematologic Cancer
NCT00006086 ·Status: COMPLETED ·Phase: PHASE1
-
CP-609,754 in Treating Patients With Advanced Solid Tumors
NCT00006085 ·Status: UNKNOWN ·Phase: PHASE1
-
Temozolomide in Treating Patients With Mycosis Fungoides or Sezary Syndrome
NCT00004106 ·Status: TERMINATED ·Phase: PHASE2
-
Nitrocamptothecin in Treating Patients With Metastatic Melanoma
NCT00005875 ·Status: COMPLETED ·Phase: PHASE2
-
Sarcosinamide Nitrosourea in Treating Patients With Metastatic or Unresectable Solid Tumors
NCT00004079 ·Status: COMPLETED ·Phase: PHASE1
-
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery
NCT00004075 ·Status: COMPLETED ·Phase: PHASE1
-
ISIS 3521 in Treating Patients With Advanced, Unresectable, or Metastatic Non-small Cell Lung Cancer or Unresectable or Metastatic Melanoma
NCT00003989 ·Status: COMPLETED ·Phase: PHASE2
-
Pyrazoloacridine in Treating Patients With Metastatic Skin or Eye Melanoma
NCT00003802 ·Status: COMPLETED ·Phase: PHASE2
-
Temsirolimus and Bryostatin 1 in Treating Patients With Unresectable or Metastatic Solid Tumors
NCT00112476 ·Status: COMPLETED ·Phase: PHASE1
-
Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
NCT00110019 ·Status: COMPLETED ·Phase: PHASE3
-
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic Malignant Melanoma
NCT00104897 ·Status: COMPLETED ·Phase: PHASE2
-
Avelumab and Trabectedin in Treating Patients With Liposarcoma or Leiomyosarcoma That is Metastatic or Cannot Be Removed by Surgery
NCT03074318 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Azacitidine and Recombinant Interferon Alfa-2b in Treating Patients With Stage III or Stage IV Melanoma or Stage IV Kidney Cancer That Cannot Be Removed By Surgery
NCT00217542 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Locally Advanced or Metastatic Cancer of the Esophagus
NCT00030862 ·Status: COMPLETED ·Phase: PHASE2
-
Nitrocamptothecin in Treating Patients With Soft Tissue Sarcomas
NCT00005874 ·Status: COMPLETED ·Phase: PHASE2
-
Flavopiridol and Irinotecan in Treating Patients With Advanced Solid Tumors
NCT00006485 ·Status: COMPLETED ·Phase: PHASE1
-
Sorafenib in Treating Patients With Advanced Malignant Solid Tumors
NCT00810394 ·Status: COMPLETED ·Phase: PHASE2
-
Cediranib Maleate in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By Surgery
NCT00309946 ·Status: COMPLETED ·Phase: PHASE2
-
Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
NCT01375829 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1