ISIS 3521 in Treating Patients With Advanced, Unresectable, or Metastatic Non-small Cell Lung Cancer or Unresectable or Metastatic Melanoma
NCT00003989 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 50
Last updated 2012-07-11
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of ISIS 3521 in treating patients who have advanced, unresectable, or metastatic non-small cell lung cancer or unresectable or metastatic melanoma.
Conditions
- Lung Cancer
- Melanoma (Skin)
Interventions
- BIOLOGICAL
-
ISIS 3521
Sponsors & Collaborators
-
European Organisation for Research and Treatment of Cancer - EORTC
lead NETWORK
Principal Investigators
-
Shoshana Kaplan, MD · Universitaetsspital-Basel
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-06-30
Countries
- Austria
- Belgium
- Denmark
- France
- Germany
- Netherlands
- Norway
- Switzerland
- United Kingdom
Study Locations
More Related Trials
-
Sorafenib in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed By Surgery
NCT00119249 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide in Patients With Progressive or Recurrent Non-small Cell Lung Cancer
NCT00003062 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery
NCT00521001 ·Status: COMPLETED ·Phase: PHASE2
-
Everolimus in Treating Patients With Stage IV Melanoma
NCT00098553 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Trial of Neoadjuvant Temozolomide in Melanoma Patients With Palpable Stage III or IV Disease Undergoing Complete Surgical Resection
NCT00588341 ·Status: COMPLETED ·Phase: PHASE2
-
MEK Inhibitor AZD6244 in Treating Patients With Stage III or Stage IV Melanoma
NCT00866177 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Therapeutic Drug Monitoring-Based Atezolizumab Dosing
NCT06066138 ·Status: RECRUITING ·Phase: PHASE1
-
Gamma-secretase/Notch Signalling Pathway Inhibitor RO4929097 in Combination With Cisplatin, Vinblastine, and Temozolomide in Treating Patients With Recurrent or Metastatic Melanoma
NCT01196416 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable Melanoma
NCT01851408 ·Status: WITHDRAWN ·Phase: PHASE2
-
Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma
NCT00509041 ·Status: COMPLETED ·Phase: PHASE2
-
Pyrazoloacridine in Treating Patients With Metastatic Skin or Eye Melanoma
NCT00003802 ·Status: COMPLETED ·Phase: PHASE2
-
AZD2171 in Treating Patients With Refractory Metastatic Kidney Cancer
NCT00303862 ·Status: TERMINATED ·Phase: PHASE2
-
Phase 2 Study of the Poly(ADP-Ribose) Polymerase Inhibitor E7016 in Combination With Temozolomide in Subjects With Wild Type BRAF Stage IV or Unresectable Stage III Melanoma
NCT01605162 ·Status: TERMINATED ·Phase: PHASE2
-
Tanespimycin in Treating Patients With Stage III-IV Melanoma
NCT00087386 ·Status: TERMINATED ·Phase: PHASE2
-
Cediranib Maleate in Treating Patients With Malignant Mesothelioma That Cannot Be Removed By Surgery
NCT00309946 ·Status: COMPLETED ·Phase: PHASE2
-
Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer
NCT04919382 ·Status: RECRUITING ·Phase: PHASE2
-
Bortezomib With or Without Irinotecan in Treating Patients With Locally Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT00103259 ·Status: COMPLETED ·Phase: PHASE2
-
Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare Tumors
NCT03108131 ·Status: COMPLETED ·Phase: PHASE2
-
Gefitinib and Docetaxel in Treating Patients With Advanced Solid Tumors
NCT00084786 ·Status: COMPLETED ·Phase: PHASE1
-
Temozolomide in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-small Cell Lung Cancer
NCT00005037 ·Status: COMPLETED ·Phase: PHASE2
-
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic Malignant Melanoma
NCT00104897 ·Status: COMPLETED ·Phase: PHASE2
-
Disulfiram Plus Arsenic Trioxide In Patients With Metastatic Melanoma and at Least One Prior Systemic Therapy
NCT00571116 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of Disitamab Vedotin With Other Anticancer Drugs in Solid Tumors
NCT06157892 ·Status: RECRUITING ·Phase: PHASE2
-
Carboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by Surgery
NCT00110019 ·Status: COMPLETED ·Phase: PHASE3
-
Vorinostat in Treating Patients With Metastatic or Unresectable Melanoma
NCT00121225 ·Status: COMPLETED ·Phase: PHASE2