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Intra-abdominal Pressure and Dynamic Preload Variables

NCT02690688 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2016-02-24

No results posted yet for this study

Summary

Dynamic preload variables like pulse-pressure and stroke volume variation may be used to predict fluid responsiveness in patients during controlled ventilation. Previous work has shown that a rapid decrease in intra-abdominal pressure may lead to an increase in dynamic preload parameters, suggestive of a fluid deficit - despite fluid status had not changed \[van Lavieren M 2014\].

The results of this study are limited by the fact that a non-invasive and uncalibrated hemodynamic monitoring system (Nexfin™) was used.

The present study thus aims to evaluate the effects of abdominal pressure changes on dynamic preload parameters (PPV and SVV) employing conventional, invasive hemodynamic monitoring (Vigileo®, Edwards Lifescience) in open abdominal surgery as well as in minimal invasive surgical procedures with pneumoperitoneum.

Conditions

  • Pneumoperitoneum

Interventions

DEVICE

determination of dynamic preload variables

Sponsors & Collaborators

  • University of Luebeck

    lead OTHER

Principal Investigators

  • Matthias Heringlake, MD · Professor of Anesthesiology, Deputy Director Cardiac Anesthesia, Dept. of Anesthesiology University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-03-31
Primary Completion
2017-03-31
Completion
2017-07-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02690688 on ClinicalTrials.gov