B-type Natriuretic Peptide Guided Therapy to Improve Clinical Outcomes for Patients Undergoing Non-cardiac Surgery
NCT02679859 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2016-02-11
Summary
The primary hypothesis of the BETTER pilot trial is that B-type natriuretic peptide (BNP) directed medical therapy prior to noncardiac surgery will be associated with improved cardiovascular outcomes, when compared to standard of care.
Conditions
- Surgery
- Cardiovascular Complications
- Risk Assessment
Interventions
- OTHER
-
BNP guided medical therapy optimisation
Sponsors & Collaborators
-
University of Stellenbosch
collaborator OTHER -
University of KwaZulu
lead OTHER
Principal Investigators
-
Bruce Biccard, MD, PhD · University of Cape Town
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- SINGLE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-07-31
- Primary Completion
- 2018-06-30
- Completion
- 2018-07-31
More Related Trials
-
Preoperative BNP as Biomarker of Postoperative Cardiovascular Complications
NCT02570607 ·Status: COMPLETED
-
Optimization of Hepatic Hemodynamics During Liver Surgery
NCT02993640 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
A Comparison of Two Target Mean Arterial Pressures in the Resuscitation of Hypotensive Trauma Patients
NCT00459160 ·Status: UNKNOWN ·Phase: NA
-
ANG-First Trial (Angiotensin II as First-Line Vasopressor Therapy in Cardiac Surgery)
NCT06487585 ·Status: RECRUITING ·Phase: PHASE4
-
Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.
NCT02836899 ·Status: COMPLETED ·Phase: PHASE3
-
NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock
NCT00736723 ·Status: COMPLETED
-
Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury
NCT06349577 ·Status: RECRUITING ·Phase: NA
-
Measurement Of NT-proBNP to Predict Outcomes in Surgery
NCT04014647 ·Status: SUSPENDED
-
Bilevel Positive Airway Pressure in Cardiac Surgery
NCT02600182 ·Status: COMPLETED ·Phase: NA
-
Perioperative Personalized Blood Pressure Management
NCT04894045 ·Status: COMPLETED ·Phase: NA
-
Permissive Hypotension After Cardiac Surgery
NCT06476613 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Cardiovascular Outcomes and Mortality in Vascular Surgical Patients
NCT05208957 ·Status: COMPLETED
-
Tight Closed-loop Systolic Arterial Pressure Control
NCT04357301 ·Status: COMPLETED ·Phase: NA
-
Brain Autoregulation Research Study
NCT07221721 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Limiting IV Chloride to Reduce AKI After Cardiac Surgery
NCT02020538 ·Status: COMPLETED ·Phase: NA
-
Impact of Intraoperative Blood Pressure Components on Postoperative AKI: A Phenotype-Stratified Analysis
NCT07156474 ·Status: NOT_YET_RECRUITING
-
Controling Mean Arterial Pressure Using a Closed-Loop System for Vasopressor Titration
NCT04586218 ·Status: COMPLETED ·Phase: NA
-
Blood Conservation in Patients (3.5-12kg) Undergoing Congenital Cardiac Surgery
NCT05881564 ·Status: RECRUITING ·Phase: NA
-
Parameters of Cerebral Perfusion
NCT02806492 ·Status: COMPLETED ·Phase: NA
-
Perioperative Individualized Optimization of Mean Arterial Pressure in Cardiac Surgery
NCT05403697 ·Status: TERMINATED ·Phase: NA
-
Ankle Brachial Index Versus Conventional Cardiac Risk Indices
NCT03122600 ·Status: UNKNOWN
-
Evaluation of the Brain Natriuretic Peptide as a Predictor of Morbidity and Mortality in Cardiac Surgery
NCT00699673 ·Status: UNKNOWN
-
Effect of High vs. Low MAP Levels on Clinical Outcomes in Elderly Patients During Noncardiothoracic Surgery
NCT02857153 ·Status: UNKNOWN ·Phase: NA
-
Vasopressin to Prevent Hypotension During Beach Chair Surgery
NCT01687894 ·Status: COMPLETED
-
This is an Observational Study That Aims to Demonstrate Postoperative Risk Factors in Pediatric Cardiac Surgery
NCT06985082 ·Status: NOT_YET_RECRUITING