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Pain In Neuropathy Study

NCT02672059 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 700

Last updated 2019-09-17

No results posted yet for this study

Summary

In the context of peripheral neuropathy, we will aim to elucidate correlates between sensory symptoms and:

* Sensory nerve dysfunction.
* Cutaneous small nerve fibre innervation density.
* Psychological co-morbidity.
* Circadian rhythm disturbance co-morbidity.
* Functionality and Quality of life.
* Patterns of human brain activity in a subset of patients that consent to participate in the FMRI (functional magnetic resonance imaging) component of PINS.

2\. We will also collect blood samples in this phenotyped cohort of patients. These blood samples coupled with detailed phenotype data will investigate potential gene associations only in the development of painful neuropathy.

3\. Knowledge gained from the study will be used to aid the further development of pain questionnaires, designed to detect patients with painful neuropathy.

4.Knowledge gained from the study will be invaluable in informing on-going investigations of painful peripheral neuropathy in animal models, both in our laboratory and others.

Conditions

  • Diabetic Neuropathy
  • Neuropathic Pain
  • Chronic Pain
  • Carpal Tunnel Syndrome
  • Peripheral Neuropathies

Interventions

OTHER

Observation

No intervention

Sponsors & Collaborators

  • University of Oxford

    collaborator OTHER

  • Imperial College London

    collaborator OTHER

  • Sheffield Teaching Hospitals NHS Foundation Trust

    collaborator OTHER

  • King's College London

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-02-28
Primary Completion
2021-06-30

Countries

  • United Kingdom

Study Locations

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Diseases
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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02672059 on ClinicalTrials.gov