Study of ADCT-402 in Patients With Relapsed or Refractory B-cell Lineage Non Hodgkin Lymphoma (B-NHL)
NCT02669017 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 183
Last updated 2021-05-19
Summary
This study evaluates ADCT-402 in participants with Relapsed or Refractory B-cell Lineage Non Hodgkin Lymphoma (B-NHL). Participants will participate in a dose escalation phase (Part 1) and dose expansion (Part 2). In Part 2, participants will receive the dose level identified in Part 1.
Conditions
- Non-Hodgkin Lymphoma
- Burkitt's Lymphoma
- Chronic Lymphocytic Leukemia
- Lymphoma, Large B-Cell, Diffuse
- Lymphoma, Follicular
- Lymphoma, Mantle-Cell
- Lymphoma, Marginal Zone
- Waldenstrom Macroglobulinemia
- Primary Mediastinal B-cell Lymphoma
Interventions
- DRUG
-
ADCT-402
intravenous infusion
Sponsors & Collaborators
-
ADC Therapeutics S.A.
lead INDUSTRY
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-03-31
- Primary Completion
- 2019-02-21
- Completion
- 2019-02-21
Countries
- United States
- Italy
- United Kingdom
Study Locations
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