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Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain

NCT02667821 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2017-10-10

Study results available
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Summary

The Investigators are performing a study to determine, in patients with chronic/recurrent neck pain, the cerebrovascular hemodynamic consequences of cervical spine movements, including manipulation, in vivo using fMRI technology on vertebral and cranial blood flow dynamics affecting brain perfusion, and extend the current data set on these variables

Conditions

  • Vertebral Artery Dissection
  • Cerebrovascular Accident
  • Stroke

Interventions

OTHER

Head positions and spinal manipulation

Each participant will undergo three separate test maneuvers. Neutral (0° rotation) neck position (condition 1) will be followed by block randomization between maximum voluntary rotation (condition 2) and a high-velocity-low-amplitude cervical manipulation targeted at C1-C2 (condition 3). Conditions 1 and 2 will be held for 1 minute before returning to neutral alignment. For the manipulation, the head will be repositioned at neutrality immediate. An experienced practitioner will perform the manipulation on the adjustable and pivotal MRI bed. After each condition, MRI of the upper neck and cerebrum for perfusion and blood flow will ensue.

Sponsors & Collaborators

  • National Chiropractic Mutual Insurance Company (NCMIC)

    collaborator UNKNOWN

  • Canadian Memorial Chiropractic College

    lead OTHER

Principal Investigators

  • Greg Wells, PhD · University of Toronto

  • Nicholas Moser, BSc, Dc · Canadian Memorial Chiropractic College

  • John J Triano, DC, PhD · Canadian Memorial Chiropractic College

  • Michael Noseworthy, PhD · McMaster University

  • Silvano Mior, DC, PhD · Canadian Memorial Chiropractic College

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-06-30
Primary Completion
2017-05-31
Completion
2017-05-31

Countries

  • Canada

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02667821 on ClinicalTrials.gov