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Changes in Cerebral Blood Flow With Spinal Manipulative Therapy vs. Voluntary Motion

NCT01205490 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2011-06-28

No results posted yet for this study

Summary

The investigators are performing a study to determine whether changes in blood flow occur in the neck and back of the brain following a series of head positions and a manipulation of the upper neck. Each participant will be asked to undergo a series of MRI's to evaluate whether there are any changes in blood flow resulting from any of the head positions or manipulation. The study will be conducted over a period of 1 day and each participant can anticipate the testing to take approximately 120 minutes.

Conditions

  • Vertebral Artery Dissection
  • Cerebrovascular Accident
  • Cerebrovascular Stroke

Interventions

OTHER

head positions and spinal manipulation

Each subject will then undergo a baseline MRI in a head neutral position (0 degrees rotation). They will then be placed in head rotation (45 degrees) to the non-dominant and undergo a MRI. Maximum rotation to the side with MRI will follow. Finally, each subject will receive an upper cervical rotary manipulation to the non-dominant side with MRI immediately after. A total of 4 test conditions will be evaluated (rest, 45 degree, maximal, post-manipulation). The manipulation will be performed by an experience practitioner on a bed just outside the MRI room in supine position. A controlled impulse load will be applied and the head/neck returned to neutral position. Prior to each maneuver, the subject will be queried on their comfort, condition and willingness to continue

Sponsors & Collaborators

  • Canadian Medical Protective Association

    collaborator OTHER

  • NCMIC

    collaborator UNKNOWN

  • Canadian Memorial Chiropractic College

    lead OTHER

Principal Investigators

  • Greg Wells, PhD · University of Toronto

  • Jairus Quesnele, BSc, DC · Canadian Memorial Chiropractic College

  • John J Triano, DC, PhD · Canadian Memorial Chiropractic College

  • Michael Noseworthy, PhD · McMaster University

Study Design

Purpose
BASIC_SCIENCE
Masking
SINGLE

Eligibility

Min Age
18 Years
Max Age
35 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-07-31
Primary Completion
2012-08-31
Completion
2012-08-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01205490 on ClinicalTrials.gov