Aerobic Exercise and Brain Health in Multiple Sclerosis
NCT02661555 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 86
Last updated 2021-06-03
Summary
The purpose of the project is to investigate how aerobic exercise affects brain volume, specific brain regions, neurotrophins and cognition in patients with multiple sclerosis.
The study will be a single blinded randomized controlled trial with a 6 months intervention.
It is hypothesized that aerobic exercise can slow down brain atrophy, increase the size of hippocampus, upregulate the secretion of neurotrophins and improve cognitive performance in people with multiple sclerosis.
Conditions
- Multiple Sclerosis
- Brain Atrophy
- Cognitive Impairment
Interventions
- OTHER
-
Aerobic exercise
Sponsors & Collaborators
-
Jascha Fonden
collaborator OTHER -
Knud and Edith Eriksens memorial fund
collaborator UNKNOWN -
University of Southern Denmark
collaborator OTHER -
Augustinus fund
collaborator UNKNOWN -
Masku Neurological Center
collaborator UNKNOWN -
University of Aarhus
lead OTHER
Principal Investigators
-
Martin L Christensen, MSc · University of Aarhus
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2016-01-31
- Primary Completion
- 2018-08-31
- Completion
- 2019-05-31
Countries
- Denmark
Study Locations
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