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Oxidative Stress in OR Personnel

NCT02654834 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2018-01-25

No results posted yet for this study

Summary

The purpose of this study is investigate to the effect(s) of chronic occupational exposure to N20 and volatile anesthetics on the extent of oxidative stress (DNA damage and the generation of the biochemical markers) in operating room staff, with different levels of exposure to halogenated hydrocarbons, in comparison to unexposed controls (Intensive Care Staff), and to determine the relationship between the degree of oxidative stress and psychological stress, as assessed by validated psychometric measures.

Conditions

  • Oxidative Stress

Interventions

OTHER

Exposure to nitrous oxide or other volatile anesthetics

No intervention, but routine work-place exposure to volatile anesthetics

Sponsors & Collaborators

  • Nationwide Children's Hospital

    lead OTHER

Principal Investigators

  • Haleh Saadat, MD · Nationwide Children's Hospital

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-05-31
Primary Completion
2016-03-31
Completion
2016-03-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02654834 on ClinicalTrials.gov