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Propofol/Dexmedetomidine Versus Desflurane Effects on Post Hepatectomy Hepatocellular Injury

NCT05246371 · Status: UNKNOWN · Phase: EARLY_PHASE1 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2023-01-18

No results posted yet for this study

Summary

This study will compare the effects of propofol/dexmedetomidine versus desflurane for maintenance of general anesthesia on hepatocellular injury in patients undergoing partial hepatectomy.

Conditions

  • Hepatectomy

Interventions

DRUG

Propofol, dexmedetomidine

Patients will receive maintenance of general anesthesia by TIVA using combination of propofol and dexmedetomidine.

DRUG

Desflurane

Patients will receive maintenance of general anesthesia by desflurane.

Sponsors & Collaborators

  • Ain Shams University

    lead OTHER

Principal Investigators

  • Hany Alzahaby, Professor · Ain Shams University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-06-01
Primary Completion
2021-11-01
Completion
2023-11-30

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05246371 on ClinicalTrials.gov