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Fibrocytes in Early and Longstanding Rheumatoid Arthritis

NCT02652299 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2019-03-13

No results posted yet for this study

Summary

This study will focus on a rare cell population called fibrocytes in peripheral blood and synovial tissue in Rheumatoid Arthritis (RA). One group of patients with early RA and one group with long-standing RA. Both groups will be followed for 6 months.

After informed and written consent a control groups is also formed: One for synovial biopsies for patients undergoing a routine arthroscopy, where a peripheral blood sample is also taken.

The hypothesis is that fibrocytes are present in the blood and synovial tissue in RA. Patients with early and long-standing RA have higher concentrations of fibrocytes in peripheral blood and synovial tissue compared to a control groups. Levels of fibrocytes in peripheral blood and synovial tissue are correlated with RA disease activity measures and imaging findings.

Conditions

Interventions

BIOLOGICAL

Synovial biopsy

Synovial tissue for analysis and biobank.

Sponsors & Collaborators

  • Odense University Hospital

    lead OTHER

Principal Investigators

  • Søren Andreas Just, MD · Odense University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-03-31
Primary Completion
2018-04-04
Completion
2018-04-04

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02652299 on ClinicalTrials.gov