MedTrace Logo

The Effects of the Anesthetic Ketamine in Young Children Undergoing Procedural Sedation

NCT02650154 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 70

Last updated 2016-10-18

No results posted yet for this study

Summary

In the emergency department (ED), ketamine is a popular anesthetic agent during sedation of children for painful and other short procedures. Sedation for procedures is more commonly used in children than adults, to achieve motion control and cooperation. In children, ketamine offers an ideal choice due to the fact that it is short acting, a highly effective sedative, and preserves cardio-respiratory stability. In the United States, more than one million children per year up to four years of age undergo short procedures requiring anesthestic agents, including ketamine. However, there is mounting concern from animal studies and retrospective human research regarding the safety of ketamine when administered to infants and young children with respect to its potential toxic effects on the developing . Conversely, ketamine has also been suggested as a neuroprotective agent. Prompt investigation and resolution of this issue is urgently required.

Conditions

Sponsors & Collaborators

  • University of Toronto

    collaborator OTHER

  • The Hospital for Sick Children

    lead OTHER

Principal Investigators

  • Yaron Finkelstein, MD · The Hospital for Sick Children

Eligibility

Min Age
3 Months
Max Age
48 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-08-31
Primary Completion
2016-02-29
Completion
2016-02-29

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02650154 on ClinicalTrials.gov