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Optimal Dosing of Ketamine for Procedural Sedation and Analgesia in Children

NCT02519595 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 182

Last updated 2016-10-12

Study results available
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Summary

There is a wide variation of published IV ketamine dosing regimens used for procedural sedation in children in the Emergency Department (ED). The purpose of the study was to compare the efficacy, duration of sedation and adverse events between the three commonly administered doses of IV ketamine (1 mg/kg, 1.5 mg/kg and 2 mg/kg) using the traditional administration method of 30-60 second infusion for ED sedation in children.

Conditions

  • Moderate, Deep Sedation

Interventions

DRUG

Ketamine IV 1mg/kg

Intervention: Ketamine IV 1mg/kg

DRUG

Ketamine IV 1.5mg/kg

Intervention: Ketamine IV 1.5 mg/kg

DRUG

Ketamine IV 2mg/kg

Intervention: Ketamine IV 2 mg/kg

Sponsors & Collaborators

  • Children's Hospital of Michigan

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
3 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2010-08-31
Primary Completion
2012-08-31
Completion
2012-08-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02519595 on ClinicalTrials.gov