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Pupillary Dilation After Incremental Tetanic Stimulations Under Ketamine Sedation

NCT02648412 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2016-12-22

No results posted yet for this study

Summary

The aim of the study was to describe the relationship between the intensity of a standardized tetanic stimulation and the associated reflex pupillary dilation in patients under ketamine sedation.

After an intravenous bolus of 1 mg/kg of ketamine, tetanic stimulations were performed every minute at increasing intensities of 10, 20, 30, 40 and 60 milliamps (similar to the stimulations of neuromuscular blocking agents monitoring). Pupillary diameter was measured before and after each stimulation.

Conditions

Interventions

DRUG

ketamine

bolus 1 mg/kg

PROCEDURE

Tetanic stimulations of incremental intensities

10-20-30-40-60 milliamps on the patient's left forearm

Sponsors & Collaborators

  • Pr Isabelle CONSTANT

    lead OTHER

Principal Investigators

  • Isabelle Constant, PHD · University Hospital Armand Trousseau

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
2 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-04-30
Primary Completion
2013-01-31
Completion
2013-04-30

Countries

  • France

Study Locations

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Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02648412 on ClinicalTrials.gov