Pre-existing Kinase Domain Mutations in Ph-positive Leukemias

NCT02643888 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2022-10-31

No results posted yet for this study

Summary

The main task of this study includes analyses of the BCR-ABL1 (breakpoint cluster region/Abelson) gene and mutations in the BCR-ABL1 tyrosine kinase domain within flow-sorted stem cells from the bone marrow and/or peripheral blood specimens. To assess the germline configuration of the patient, DNA from fingernail clippings will be investigated.

Conditions

Sponsors & Collaborators

  • Medical University of Vienna

    collaborator OTHER
  • National Research Center for Radiation Medicine in Kiev

    collaborator UNKNOWN
  • St. Petersburg State Pavlov Medical University

    collaborator OTHER
  • UHKT Prague

    collaborator UNKNOWN
  • St. Anna Kinderkrebsforschung

    lead OTHER

Principal Investigators

  • Thomas Lion, MD PhD Prof · Children´s Cancer Research Institute

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-12-31
Primary Completion
2023-01-31
Completion
2023-05-31

Countries

  • Austria

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02643888 on ClinicalTrials.gov