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The Effect of Coffee Consumption in Enhancing Recovery of Bowel Function Following Colorectal Surgery.

NCT02639728 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2022-11-21

No results posted yet for this study

Summary

The effects of coffee have been shown to act as a colonic stimulant. Caffeinated coffee stimulates colonic activity, most notably in the transverse/descending colon, in magnitude similar to a meal, 60% stronger than water, and 23% stronger than decaffeinated coffee. \[1\] Moreover, the consumption of both water and caffeine causes a decrease in the rectal sensory threshold for the desire to defecate, while anal sphincter pressure after caffeine intake is significantly higher than after water intake. This may result in an earlier desire to defecate. \[2\] Coffee has also been shown to have an effect on defecation by increasing rectal tone by 45% (measured with a barostat) thirty minutes after consumption. \[3\]

Conditions

  • Postoperative Ileus

Interventions

OTHER

Regular Coffee

Regular coffee will be given a 4oz cup three times daily and will be instructed to consume all of its liquid contents.

OTHER

Decaffeinated coffee

Decaffeinated coffee will be given a 4oz cup three times daily and will be instructed to consume all of its liquid contents.

OTHER

Warm water

Warm water will be given a 4oz cup three times daily and will be instructed to consume all of its liquid contents.

Sponsors & Collaborators

  • Cedars-Sinai Medical Center

    lead OTHER

Principal Investigators

  • Yosef Nasseri, MD · Cedars-Sinai Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-11-30
Primary Completion
2022-03-23
Completion
2022-03-23

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02639728 on ClinicalTrials.gov