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Postoperative Opioid Use and Ileus Occurrence---A Case Control Study

NCT05262569 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 596

Last updated 2022-08-09

No results posted yet for this study

Summary

Postoperative ileus (POI) is a significant complication after colorectal surgery, with reported incidence ranging from 10\~30%, leading to increased morbidity, hospital length of stay, and thus medical cost. To determine the risk factors for POI is one of the key elements for Enhanced Recovery after Surgery protocol. Increased perioperative opioid usage has been proposed as an independent risk factor for postoperative ileus, as perioperative opioid minimization has proposed to be an effective measure to decrease the incidence of POI. Although opioids are widely used to attenuate stress during surgery, and represent the cornerstone of pain treatment, anesthesiologists are strive to minimize opioid use to decrease opioid-related GI side effects. In this study, the investigators aim to find out the general occurrence of POI in the laparoscopic colorectal surgery and the effects of the postoperative opioid usage on this outcome. The strategies of opioid minimization was also investigated.

Conditions

  • Ileus
  • Opioid Use

Interventions

OTHER

ileus

retrospectively allocation according to a postoperative outcome-ileus

Sponsors & Collaborators

  • Peking University People's Hospital

    lead OTHER

Principal Investigators

  • Juhui, Dr. · Peking University People's Hospital, Beijing, China

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-04-01
Primary Completion
2022-05-31
Completion
2022-06-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05262569 on ClinicalTrials.gov