Can Optic Nerve Sheath Diameter Measurement Predict Negative Neurological Outcome ?

Summary

This study is designed as a multicenter, prospective, cohort clinical study. The out of hospital cardiac arrest (OHCA) patients presenting to the adult emergency departments of the participating hospitals will render the study population. The non-traumatic, non-intracranial event related OHCA patients in whom the return of spontaneous circulation (ROSC) is achieved will render the sampling group.

The primary aim of this study is to evaluate the relationship of bedside ultrasound (USG) measurements of Optic Nerve Sheath Diameter (ONSD) following the ROSC after Cardiopulmonary resuscitation (CPR) for OHCA patients, with early (3rd day) neurological evaluation and 30 days survival rate, proposing that increased ONSD may be related to negative neurological outcomes. Considering a relationship is found, the secondary goals of the study are established as, identifying a cut-off value for ONSD related to negative neurological outcome and the optimal time to measure ONSD.

The sampling size with a power of 95% is calculated to be 203 patients. The patients whose available next of kin has given consent will be admitted to the study.

Conditions

• Out of Hospital Cardiac Arrest
• Neurologic Symptoms

Interventions

OTHER

Ultrasonographic Measurements of Optic Nerve Sheath Diameter

Bedside Ultrasonographic Measurements of Optic Nerve Sheath Diameter

Sponsors & Collaborators

• Emergency Medicine Association of Turkey

  lead OTHER

Principal Investigators

• Aslıhan Yürüktümen Ünal, Ass. Prof. · Depertment Of Emergency Medicine, Akdeniz University, Antalya

• Erkan Göksu, Ass. Prof. · Depertment Of Emergency Medicine, Akdeniz University, Antalya

• Faruk Güngör, MD · Depertment Of Emergency Medicine, Antalya Education and Research Hospital, Antalya

• Betül Günalp, Ass. Prof · Depertment Of Emergency Medicine, Başkent University, Adana

• Alten Oskay, MD · Depertment Of Emergency Medicine, Denizli State Hospital, Denizli

• Mert Özen, MD · Depertment Of Emergency Medicine, Denizli State Hospital, Denizli

• Başak Bayram, Assist. Prof · Depertment Of Emergency Medicine, Dokuz Eylul University, İzmir

• Funda Karbek Akarca, Assist. Prof · Depertment Of Emergency Medicine, Ege University, İzmir

• İlhan Uz, MD · Depertment Of Emergency Medicine, Ege University, İzmir

• Nurdan Ergün Acar, Ass. Prof · Depertment Of Emergency Medicine, Eskisehir Osmangazi University, Eskisehir

• Mustafa E. Çanakçı, Resident · Depertment Of Emergency Medicine, Eskisehir Osmangazi University, Eskisehir

• Bülent Erbil, Ass. Prof. · Depertment Of Emergency Medicine, Hacettepe University, Ankara

• Mehmet A. Karaca, Ass. Prof. · Depertment Of Emergency Medicine, Hacettepe University, Ankara

• Özgür Dikme, MD · Depertment Of Emergency Medicine, Istanbul Education and Research Hospital, Istanbul

• Adnan Yamanoglu, MD · Depertment Of Emergency Medicine, Istanbul Haseki Education and Research Hospital, Istanbul

• Özgür Cevrim, MD · Depertment Of Emergency Medicine, Istanbul Sıslı Hamidiye Etfal Education and Research Hospital, Istanbul

• Cem Ertan, Ass. Prof. · Depertment Of Emergency Medicine, Izmır University, İzmir

• Tanzer Korkmaz, Assist. Prof · Depertment Of Emergency Medicine, Izmır University, İzmir

• Murat Yeşilaras, MD · Depertment Of Emergency Medicine, Izmır Tepecik Education and Research Hospital, Izmir

• Turgay Y. Kılıç, MD · Depertment Of Emergency Medicine, Izmır Tepecik Education and Research Hospital, Izmir

• Mehmet A. Aslaner, MD · Depertment Of Emergency Medicine, Nevşehir State Hospital, Nevşehir

• Salih Ekinci, MD · Depertment Of Emergency Medicine, Koc University, İstanbul

• Onur Karakayalı, MD · Depertment Of Emergency Medicine, Kocaeli Derince Education and Research Hospital, Kocaeli

• Ali Batur, MD · Depertment Of Emergency Medicine, Erzurum Education and Research Hospital, Erzurum

• Volkan Arslan, MD · Depertment Of Emergency Medicine, Ankara Education and Research Hospital, Ankara

• Davut Kaplan, MD · Depertment Of Emergency Medicine, Yunus Emre State Hospital, Eskişehir

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2015-12-31

Primary Completion

2017-02-28

Completion

2017-03-31

Countries

• Turkey (Türkiye)

Study Locations