Anti-inflammatory Effect of Therapeutic Hypothermia in Out-hospital Cardiac Arrest Patients With Cardiogenic Shock
NCT02633358 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 141
Last updated 2019-08-07
Summary
Acute myocardial infarction complicated with cardiogenic shock trigger IL-6, the strong inflammatory response, result in multiple organ failure, even death.
While therapeutic hypothermia,to expect the possibility of anti-inflammatory effect via IL-6 bi-phasic effect and IL-10 , to improve the multiple organ failure, to increase survival rate and well cerebral performance.
Conditions
- Cardiac Arrest
Interventions
- DEVICE
-
Therapeutic hypothermia group
Therapeutic hypothermia
Sponsors & Collaborators
-
China Medical University Hospital
lead OTHER
Principal Investigators
-
Da-Long Chen, Master · Chnia Medical University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 100 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2015-11-01
- Primary Completion
- 2018-08-18
- Completion
- 2018-08-18
Countries
- Taiwan
Study Locations
More Related Trials
-
Effect of Targeted Temperature Management on Cerebral Autoregulation in Patients With Neurocritical Diseases
NCT04728438 ·Status: UNKNOWN
-
IL Ancillary Study of the Therapeutic Hypothermia After Nonshockable Cardiac Arrest Trial.
NCT02711098 ·Status: COMPLETED ·Phase: PHASE3
-
A Prospective Analysis of the Effect of Therapeutic Hypothermia After Cardiac Arrest
NCT00676598 ·Status: COMPLETED
-
Cerebral Oxymetry and Neurological Outcome in Therapeutic Hypothermia
NCT03024021 ·Status: COMPLETED
-
Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction
NCT01890317 ·Status: COMPLETED ·Phase: NA
-
Pilot Community Clinical Study of Hypothermia in Cardiac Arrest
NCT00329563 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Hypothermia as an Adjunctive Therapy to Percutaneous Intervention in Patients With Acute Myocardial Infarction
NCT02664194 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of MTH in PCI Under VA-ECMO for AMICS
NCT07186972 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Transnasal Induction of Normothermia in Febrile Stroke Patients
NCT03360656 ·Status: COMPLETED ·Phase: NA
-
Intra-arrest Therapeutic Hypothermia in Prehospital Cardiac Arrest
NCT00886184 ·Status: COMPLETED ·Phase: NA
-
Impact of Speed Of Rewarming After CaRdiac Arrest and ThErapeutic Hypothermia
NCT02555254 ·Status: COMPLETED ·Phase: NA
-
Safety and Feasibility of Endovascular Cooling Device in Patients With Hypothermic Cardiopulmonary Resuscitation
NCT00154674 ·Status: UNKNOWN ·Phase: NA
-
Neurological Prognostication of Patients in Therapeutic Hypothermia After Cardiac Arrest
NCT02390999 ·Status: COMPLETED ·Phase: NA
-
NSE Ancillary Study of The Therapeutic Hypothermia After Nonshockable Cardiac Arrest Trial.
NCT02722473 ·Status: COMPLETED ·Phase: PHASE3
-
Neuron Specific Enolase (NSE) as Outcome Parameter of Cooling Therapy After Survived Sudden Cardiac Death
NCT01102153 ·Status: COMPLETED
-
Induction of Mild Hypothermia Following Out-of-hospital Cardiac Arrest
NCT00391469 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Defibrillation in Accidental Hypothermia
NCT06131892 ·Status: COMPLETED
-
Application of an Early In-Hospital Temperature Management Protocol for Heat Stroke Patients
NCT06537557 ·Status: RECRUITING ·Phase: NA
-
A Pilot Study of Transcoronary Myocardial Cooling
NCT02312336 ·Status: COMPLETED ·Phase: NA
-
Jugular Venous Oxygen Saturation During Therapeutic Hypothermia After Cardiac Arrest
NCT00870610 ·Status: COMPLETED
-
Intracoronary Hypothermia as a Prevention of Reperfusion Injury in Myocardial Infarction.
NCT06567249 ·Status: RECRUITING ·Phase: NA
-
Hypothermia After Cardiac Arrest - Effects on Myocardial Function and Inflammatory Response.
NCT03743584 ·Status: COMPLETED ·Phase: NA
-
Mild Hypothermia in Acute Ischemic Stroke
NCT00987922 ·Status: COMPLETED ·Phase: PHASE2
-
Targeted Temperature Management After In-Hospital Cardiac Arrest
NCT02578823 ·Status: UNKNOWN ·Phase: NA
-
COOL-Trial: Outcome With Invasive and Non-invasive Cooling After Cardiac Arrest
NCT00843297 ·Status: COMPLETED ·Phase: PHASE4