Investigate the Radical Extent of Lymphadenectomy of LAparoscopic Right Colectomy for Colon Cancer(RELARC).

Summary

To investigate whether extended lymphadenectomy (CME) in laparoscopic colectomy could improve disease-free survival in patients with right colon cancer, compared with standard D2 radical operation.

Conditions

• Colon Cancer

Interventions

PROCEDURE

D2 radical operation

In D2 radical operation group(D2), the lymph node dissection is based on ligating the supplying vessels close to the right-side of superior mesenteric vein and clean up the surrounding lymph node and adipose tissue.

PROCEDURE

Complete mesocolic excision (CME)

In complete mesocolic excision group (CME), the dissecting extent includes the lymphatic and fat tissues surrounding the root of ascending mesocolon, which situated on the surface of superior mesenteric vein, and the root of right half of transverse mesocolon, which situated on the surface of pancreas neck.

Sponsors & Collaborators

• Chinese PLA General Hospital

  collaborator OTHER

• Sixth Affiliated Hospital, Sun Yat-sen University

  collaborator OTHER

• Peking University Cancer Hospital & Institute

  collaborator OTHER

• Beijing Friendship Hospital

  collaborator OTHER

• Xuanwu Hospital, Beijing

  collaborator OTHER

• Ruijin Hospital

  collaborator OTHER

• Shanghai Zhongshan Hospital

  collaborator OTHER

• The First Hospital of Jilin University

  collaborator OTHER

• Nanfang Hospital, Southern Medical University

  collaborator OTHER

• Fujian Medical University Union Hospital

  collaborator OTHER

• Peking Union Medical College

  collaborator OTHER

• Peking University People's Hospital

  collaborator OTHER

• The First Affiliated Hospital with Nanjing Medical University

  collaborator OTHER

• First Affiliated Hospital of Harbin Medical University

  collaborator OTHER

• RenJi Hospital

  collaborator OTHER

• Second Affiliated Hospital, School of Medicine, Zhejiang University

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• Peking Union Medical College Hospital

  lead OTHER

Principal Investigators

• Yi XIAO, MD · Peking Union Medical College Hospital

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Max Age

75 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-01-09

Primary Completion

2019-12-26

Completion

2022-12-26

Countries

• China

Study Locations