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Awakening in Spine Surgery: A Comparison Between Clinical Signs and Bispectral Index

NCT02174913 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 34

Last updated 2020-07-13

Study results available
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Summary

BIS is one of several equipments used to monitor depth of anesthesia.Some studies found BIS can reduce total propofol dose when being used with target controlled infusion (TCI).The objective is to compare awakening time after spine surgery between using clinical signs and bispectral index (BIS) guided target controlled infusion(TCI) of propofol in patients having neurophysiologic monitoring.

Conditions

  • Spine Diseases

Interventions

DEVICE

bispectral index

Bispectral index (BIS) is one of several technologies used to monitor depth of anesthesia.

DRUG

Target controlled infusion of propofol

TCI propofol (3-7 mcg/dL, Schnider model) is used for total intravenous anesthesia in both groups

DRUG

Fentanyl

Fentanyl 1-2 mcg/kg iv for induction and then 0.5-1.0 mcg/kg/hr infusion is used for analgesic.

DRUG

Atracurium

Atracurium 0.6 mg/kg is used for endotracheal intubation

Sponsors & Collaborators

  • Mahidol University

    lead OTHER

Principal Investigators

  • Manee Raksakietisak, MD · Mahidol University

Study Design

Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-05-31
Primary Completion
2016-02-29
Completion
2016-02-29

Countries

  • Thailand

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02174913 on ClinicalTrials.gov