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Circulating Tumour DNA (ctDNA) in Patients With Colorectal Cancer and the Relationship to Imaging Features of Extramural Venous Invasion

NCT02579278 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2024-10-17

No results posted yet for this study

Summary

This study does not involve randomization or treatment. Eligible patients have colorectal adenocarcinoma with no metastases eligible for curative surgery. A pre operative staging scan must have been completed within 6 weeks prior to surgery. Two x 20ml blood samples will be taken from each patient, one prior to and one during or within 24hrs after surgery. Patients are annually followed up to 3 years.

Conditions

Interventions

OTHER

Blood sample (mrEMVI positive patient)

Two blood samples are taken from each patient with mrEMVI positive tumours post chemoradiotherapy. One pre-surgery and one during surgery from a peripheral vein.

OTHER

Blood sample (mrEMVI negative patient)

Sponsors & Collaborators

  • Imperial College London

    lead OTHER

Principal Investigators

  • Gina Brown, MD · Imperial College London

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-11-30
Primary Completion
2026-12-31
Completion
2029-12-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02579278 on ClinicalTrials.gov