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Beyond TME Origins

NCT02292641 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 383

Last updated 2024-10-17

No results posted yet for this study

Summary

All patients with recurrent colorectal cancer in the pelvis are eligible. The original primary tumour staging scans and resected surgical specimen needs to be available. Patients' recurrence will be staged using our proposed MRI classification. We will be assessing the original primary staging scans and histopathology to learn about risk factors for recurrence. We will record treatment for the recurrence, and patients will be followed up for three years.

Conditions

  • Neoplasms
  • Adenocarcinoma
  • Carcinoma

Interventions

PROCEDURE

New Radiological Staging Classification system for patients with advanced and recurrent colorectal cancer undergoing pelvic exenterative surgery

Currently there are no validated criteria or guidelines for judging whether advanced primary or recurrent colorectal cancer can be successfully removed and for selecting which patients should undergo this form of more radical surgery as is exenterative surgery. We are proposing that by validating the detailed evaluation of imaging of the tumour distribution within the pelvis using a new radiological staging classification, this will enable clear selection criteria to be established and will improve surgical planning.

Sponsors & Collaborators

  • Pelican Cancer Foundation

    collaborator OTHER

  • Imperial College London

    lead OTHER

Principal Investigators

  • Gina Dr Brown, MD · Imperial College London

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-09-25
Primary Completion
2026-12-31
Completion
2031-12-31

Countries

  • Norway
  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02292641 on ClinicalTrials.gov