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Randomized Control Trial (RCT) of Early Palliative Care for HCC

NCT02556619 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 72

Last updated 2021-04-27

No results posted yet for this study

Summary

The purpose of this research study is to evaluate the effect of early palliative care consultation on quality of life, use of hospital resources, end-of-life care and survival among Hepatocellular Carcinoma (HCC) patients with advanced End Stage Live Disease not eligible for potentially curative or local area therapy. Half of patients will receive early palliative care at diagnosis of HCC and other half will receive palliative care when all standard therapy treatments have been exhausted.

Conditions

  • Carcinoma, Hepatocellular

Interventions

BEHAVIORAL

Early Palliative Care/Symptom Control

1. Establish palliative care goals 1. Determination of Medical Power of Attorney 2. Discuss/plan code status/advance directives 3. Document palliative care goals 2. Symptom Assessment and Control 1. Pain-treatment with opioid and non-opioid medications 2. Itching-H2 blockers, steroids 3. Nutrition-appetite stimulated with Megace, review low sodium diet 4. Ascites/edema- optimize ascites management with Lasix or Aldactone. In refractory cases intermittent paracentesis can be performed 5. Nausea- treated with anti-emetics 6. Jaundice and Body Image- counselling regarding symptoms 3. End-of-Life Care 1. Discuss religious preferences 2. Assess for distress- ensure interaction with Cancer Resource Center 3. Hospice- charity Hospice options for select patients.

Sponsors & Collaborators

  • American Cancer Society, Inc.

    collaborator OTHER

  • The University of Texas Health Science Center, Houston

    lead OTHER

Principal Investigators

  • Curtis J Wray, MD · The University of Texas Health Science Center, Houston

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-04-02
Primary Completion
2021-09-30
Completion
2021-09-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02556619 on ClinicalTrials.gov